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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. NIPBL, Nipped-B homolog (Drosophila)
Sequence ID:NM_015384
NM_133433
RefSeqGene ID:NG_006987
Entrez Gene ID:25836
Ensembl ID:ENSG00000164190

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, skin, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CORNELIA DE LANGE SYNDROME 1 

Cytogenetic Location (from UniGene)

Cytogenetic Location:5p13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 36876891 - 37065921

 Exon Info From UCSC:
NM_015384
NM_133433

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8860431IncompleteBC146821Nipped-B homolog (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_056199  NP_597677  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_015384 NP_056199   HEAT
NM_133433 NP_597677 Q6KC79 HEAT

Related Sequences

 
mRNAGenPeptSwissProt
BC033847 AAH33847 Q6KC79
BC131490 AAI31491 A2RRA7
BC146821 AAI46822 A6QL62
AK126804 BAC86701 Q6KC79
AK290347 BAF83036 A8K2T2
BX538177 CAD98051 Q6KC79
BX538178 CAD98052 Q6KC79
BX640644 CAE45790 Q6KC79
AJ627032 CAF25290 Q6KC79
AJ640137 CAG26691 Q6KC79
BK005151 DAA05331 Q6IEH8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NIPBL NP_597677 M.musculus Nipbl 71175 Gene Info NP_081983 97
R.norvegicus Nipbl 294787   NP_001099885 95
A.gambiae AgaP_AGAP009290 1280257   XP_320088 42
D.melanogaster Nipped-B 3355136   NP_001163052 42
A.thaliana EMB2773 831407   NP_001190317 30

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)