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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GTF2B, General transcription factor IIB
Sequence ID:NM_001514
Entrez Gene ID:2959
Ensembl ID:ENSG00000137947

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, stem cell, stomach, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p22-p21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 89318895 - 89357182

NM_001514 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
87158931832189319028
7169978932288889323169
99811278932556489325693
112812748932582289325968
127514088932966389329796
140915158935294389353049
151616518935716589357300

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4807599Full LengthBC020597general transcription factor IIB

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001505  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001514 NP_001505 Q00403 TFIIB
TFIIB_Zn_Ribbon

Related Sequences

 
mRNAGenPeptSwissProt
M76766 AAA61149 Q00403
S44184 AAB23144 Q00403
BC020597 AAH20597 Q00403
EU446894 ABZ92423  
AK289822 BAF82511 Q00403
AB451296 BAG70110 Q00403

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GTF2B NP_001505 M.musculus Gtf2b 229906 Gene Info NP_663521 100
R.norvegicus Gtf2b 81673   NP_112303 100
A.gambiae AgaP_AGAP009558 1271351   XP_310128 80
D.melanogaster TfIIB 34430   NP_476888 79
C.elegans ttb-1 178544   NP_503146 63
A.thaliana TFIIB 818761   NP_181694 50
A.thaliana AT3G10330 820195   NP_187644 49
S.pombe SPAC16E8.16 2542339   NP_594229 48
N.crassa NCU07289 3878292   XP_962143 44
S.cerevisiae SUA7 856201   NP_015411 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)