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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. AFF1, AF4/FMR2 family, member 1
Sequence ID:NM_005935
NM_001166693
Entrez Gene ID:4299
Ensembl ID:ENSG00000172493

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, brain, cartilage, cerebrum, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 88005269 - 88029426

 Exon Info From UCSC:
NM_005935
NM_001166693

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40074243Full LengthBC114930AF4/FMR2 family, member 1
4720485IncompleteBC017432AF4/FMR2 family, member 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005926  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001166693 NP_001160165    
NM_005935 NP_005926 P51825 AF-4

Related Sequences

 
mRNAGenPeptSwissProt
L25050 AAA36642 P51825
L13773 AAA58360 P51825
AF024541 AAC51815  
AF177236 AAD56887  
AF177237 AAD56888  
AF177238 AAF09191  
AF177239 AAF09192  
BC017432 AAH17432 Q05D98
BC114930 AAI14931 Q14C88
AK296149 BAG58888 B4DJM6
AK296243 BAG58961 B4DJU9
AK300364 BAG62103 B4DTU1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AFF1 NP_005926 M.musculus Aff1 17355 Gene Info NP_001074267 75
R.norvegicus Aff1 305152   NP_001100676 74

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)