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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. IGFBP7, insulin-like growth factor binding protein 7
Sequence ID:NM_001253835
RefSeqGene ID:NG_031877
Entrez Gene ID:3490
Ensembl ID:ENSG00000163453

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 57898403 - 57976551

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3632247Full LengthBC017201insulin-like growth factor binding protein 7
5296697Full LengthBC066339insulin-like growth factor binding protein 7

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001544  

Protein Infomation

NM_001253835 NP_001240764    
NM_001553 NP_001544 Q16270 Kazal_2

Related Sequences

L19182 AAA16187 Q16270
S75725 AAB32370 Q16270
BC017201 AAH17201 Q16270
BC066339 AAH66339 Q16270
AF540057 AAN23122  
BT006654 AAP35300 Q16270
AK303915 BAG64844 B4E1N2
AK316082 BAH14453 B7Z9W7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens IGFBP7 NP_001544 M.musculus Igfbp7 29817 Gene Info NP_032074 91
R.norvegicus Igfbp7 289560   NP_001013066 91

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)