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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. KDR, kinase insert domain receptor (a type III receptor tyrosine kinase)
Sequence ID:NM_002253
RefSeqGene ID:NG_012004
Entrez Gene ID:3791
Ensembl ID:ENSG00000128052

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HEMANGIOMA, CAPILLARY INFANTILE, SOMATICANTXR1
FLT4

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q11-q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 55944649 - 55991747

 Exon Info From UCSC:
NM_002253

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40129287Full LengthBC131822kinase insert domain receptor (a type III receptor tyrosine kinase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002244  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002253 NP_002244 P35968 EC 2.7.10.1 I-set
V-set
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L04947 AAA59459 P35968 EC 2.7.10.1
AF035121 AAB88005 P35968 EC 2.7.10.1
AF063658 AAC16450 P35968 EC 2.7.10.1
BC131822 AAI31823 P35968 EC 2.7.10.1
EU826563 ACF47599 P35968 EC 2.7.10.1
FJ899739 ACR78514 P35968 EC 2.7.10.1
AB209901 BAD93138 Q59EB0  
AK293668 BAG57114 B4DEK3  
X61656 CAA43837 P35968 EC 2.7.10.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens KDR NP_002244 M.musculus Kdr 16542 Gene Info NP_034742 87

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta