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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MYLK, myosin light chain kinase
Sequence ID:NM_053025
NM_053026
NM_053027
NM_053028
NM_053031
NM_053032
NM_005965
NM_053029
NM_053030
RefSeqGene ID:NG_029111
Entrez Gene ID:4638
Ensembl ID:ENSG00000065534

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
AORTIC ANEURYSM, FAMILIAL THORACIC 7 

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 123332889 - 123419673

 Exon Info From UCSC:
NM_053025
NM_053026
NM_053027
NM_053028
NM_053031
NM_053032

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4296486IncompleteBC017811myosin light chain kinase
6668966IncompleteBC107783myosin light chain kinase
8322508IncompleteBC113456myosin light chain kinase
8322510IncompleteBC113458myosin light chain kinase
30346535IncompleteBC064695myosin, light polypeptide kinase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_444253  NP_444256  NP_444255  NP_444260  NP_444259  NP_444254  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_053025 NP_444253 Q15746 EC 2.7.11.18 fn3
Pkinase
I-set
NM_053026 NP_444254     fn3
ig
Pkinase
I-set
V-set
Pkinase_Tyr
C2-set_2
NM_053027 NP_444255     fn3
ig
Pkinase
I-set
V-set
Pkinase_Tyr
C2-set_2
NM_053028 NP_444256     fn3
ig
Pkinase
I-set
V-set
Pkinase_Tyr
C2-set_2
NM_053031 NP_444259     ig
I-set
NM_053032 NP_444260     I-set

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U48959 AAC18423 Q15746 EC 2.7.11.18
AF069601 AAD15921 Q15746 EC 2.7.11.18
AF069602 AAD15922 Q15746 EC 2.7.11.18
AF069603 AAD15923 Q15746 EC 2.7.11.18
AF069604 AAD15924 Q15746 EC 2.7.11.18
AF096773 AAD54017 Q15746 EC 2.7.11.18
AF096774 AAD54018 Q15746 EC 2.7.11.18
AF096775 AAD54019 Q15746 EC 2.7.11.18
BC017811 AAH17811 Q05D81  
BC064420 AAH64420 Q6P2N0  
BC100761 AAI00762 Q15746 EC 2.7.11.18
BC100762 AAI00763 Q15746 EC 2.7.11.18
BC100763 AAI00764 Q6P2N0  
BC107783 AAI07784 Q3B765  
BC113456 AAI13457 Q05B98  
BC113458 AAI13459 Q05B97  
AY339601 AAQ02673 Q15746 EC 2.7.11.18
AF172084 AAQ13607 Q7Z4F4  
AY424269 AAR29061 Q15746 EC 2.7.11.18
AY424270 AAR29062 Q15746 EC 2.7.11.18
DQ642691 ABG25912 Q06S79  
DQ642692 ABG25913 Q06S79  
AB037663 BAB21504 Q15746 EC 2.7.11.18
AK314412 BAG37033 Q6P2N0  
AK314443 BAG37052 Q15746 EC 2.7.11.18
AK300610 BAG62305 B4DUE3  
X85337 CAA59685 Q15746 EC 2.7.11.18
X90870 CAA62378 Q15746 EC 2.7.11.18
Y09530 CAA70723 Q6LAL4  
CR749364 CAH18217 Q68DK3  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MYLK NP_444253 M.musculus Mylk 107589 Gene Info NP_647461 86

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)