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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CHMP2B, charged multivesicular body protein 2B
Sequence ID:NM_001244644
NM_014043
RefSeqGene ID:NG_007885
Entrez Gene ID:25978
Ensembl ID:ENSG00000083937

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
AMYOTROPHIC LATERALSCLEROSIS 17 
DEMENTIA, FAMILIAL, NONSPECIFIC 

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 87276474 - 87303076

Transcript StartTranscript EndChromosomal Start Chromosomal End
12948727641287276705
2953868728984887289939
3875818729486387295057
5826848729902487299126
6857918730255387302659
79226278730286187304696

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3460712Full LengthBC001553chromatin modifying protein 2B

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_054762  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001244644 NP_001231573    
NM_014043 NP_054762 Q9UQN3 ESCRT-III

Related Sequences

 
mRNAGenPeptSwissProt
AF151842 AAD34079 Q9UQN3
BC001553 AAH01553 Q9UQN3
EU832215 ACE86785  
EU832121 ACE87471  
JF432605 ADZ15822  
AK222654 BAD96374 Q9UQN3
AK316585 BAG38173 B2RE76
AK002165 BAG51022 B2RE76
AK002180 BAG51025 B2RE76
AK296072 BAG58830 B4DJG8
AL080122 CAB45721 Q9UQN3
CR533456 CAG38487 Q9UQN3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CHMP2B NP_054762 M.musculus Chmp2b 68942 Gene Info NP_081155 100
D.melanogaster CHMP2B 38599   NP_647947 53
C.elegans C01A2.4 182050   NP_493357 44
A.thaliana VPS2.3 839362   NP_563696 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)