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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. MCCC1, methylcrotonoyl-CoA carboxylase 1 (alpha)
Sequence ID:NM_020166
RefSeqGene ID:NG_008100
Entrez Gene ID:56922
Ensembl ID:ENSG00000078070

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
3-METHYLCROTONYL-COA CARBOXYLASE 1 DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q27Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 182733007 - 182817360

 Exon Info From UCSC:
NM_020166

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2964422Full LengthBC004187methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
2964422Full LengthBC004214methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
5259867IncompleteBC036395methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_064551  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_020166 NP_064551 Q96RQ3 EC 6.4.1.4 CPSase_L_chain
Biotin_lipoyl
Biotin_carb_C
CPSase_L_D2

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF310339 AAG50245 Q96RQ3 EC 6.4.1.4
AF310972 AAG53095 Q96RQ3 EC 6.4.1.4
BC004187 AAH04187 Q96RQ3 EC 6.4.1.4
BC004214 AAH04214 Q96RQ3 EC 6.4.1.4
AF297332 AAK67986 Q96RQ3 EC 6.4.1.4
AB029826 BAA99407 Q96RQ3 EC 6.4.1.4
AK023051 BAB14377 Q96RQ3 EC 6.4.1.4
AB209737 BAD92974 Q96RQ3 EC 6.4.1.4
AK294882 BAG57977 B4DH16  
AK295293 BAG58277 B4DHW5  
AK316428 BAH14799 B7ZAW3  
CR749608 CAH18403 Q68D27  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MCCC1 NP_064551 M.musculus Mccc1 72039 Gene Info NP_076133 85
R.norvegicus Mccc1 294972   NP_001009653 84
A.gambiae AgaP_AGAP010228 1279652   XP_319416 57
D.melanogaster CG2118 43750   NP_651896 56
C.elegans F32B6.2 177841   NP_501777 54
A.thaliana MCCA 838362   NP_849583 50
N.crassa NCU00591 3881873   XP_965731 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)