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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FLNB, Filamin B, beta
Sequence ID:NM_001164317
NM_001457
NM_001164318
NM_001164319
RefSeqGene ID:NG_012801
Entrez Gene ID:2317
Ensembl ID:ENSG00000136068

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
ATELOSTEOGENESIS, TYPE I 
ATELOSTEOGENESIS, TYPE III 
BOOMERANG DYSPLASIA 
LARSEN SYNDROME 
SPONDYLOCARPOTARSAL SYNOSTOSIS SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p14.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 57994148 - 58157975

 Exon Info From UCSC:
NM_001164317
NM_001457
NM_001164318
NM_001164319

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100061537BC156184filamin B, beta (actin binding protein 278)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001448  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001164317 NP_001157789    
NM_001164318 NP_001157790    
NM_001164319 NP_001157791    
NM_001457 NP_001448 O75369 CH
Filamin

Related Sequences

 
mRNAGenPeptSwissProt
M62994 AAA35505 O75369
AF043045 AAC33845 O75369
AF042166 AAC39842 O75369
AF238609 AAF97046 O75369
BC156184 AAI56185 O75369
AF353666 AAL68439 Q8WXT3
AB191258 BAD52434 O75369
AB209889 BAD93126 O75369
AB371580 BAG48309 O75369
AB371581 BAG48310 O75369
AB371582 BAG48311 O75369
AL137574 CAB70818 O75369
BX641085 CAE46040 O75369
CR749793 CAH18654 Q68CT4

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FLNB NP_001157789 R.norvegicus Flnb 306204   NP_001100758 96
M.musculus Flnb 286940 Gene Info NP_598841 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)