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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. IQSEC1, IQ motif and Sec7 domain 1
Sequence ID:NM_001134382
Entrez Gene ID:9922
Ensembl ID:ENSG00000144711

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p25.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 12939373 - 12983170

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2900367Full LengthBC010267IQ motif and Sec7 domain 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_055684  

Protein Infomation

NM_001134382 NP_001127854    
NM_014869 NP_055684 Q6DN90 Sec7

Related Sequences

BC010267 AAH10267 Q6DN90
AY653734 AAT72063 Q6DN90
JF432314 ADZ15531  
AB018306 BAA34483 Q6DN90
AK294525 BAG57736 B4DGC5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens IQSEC1 NP_001127854 M.musculus Iqsec1 232227 Gene Info NP_001127856 94
C.elegans M02B7.5 177142   NP_500420 46
D.melanogaster siz 40327   NP_730594 43
A.gambiae AgaP_AGAP011421 1278273   XP_317885 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)