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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. TOB2, Transducer of ERBB2, 2
Sequence ID:NM_016272
Entrez Gene ID:10766
Ensembl ID:ENSG00000183864

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 41832234 - 41833563

NM_016272 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4940977Full LengthBC028919transducer of ERBB2, 2
5786640Full LengthBC038957transducer of ERBB2, 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_057356  

Protein Infomation

NM_016272 NP_057356 Q14106 PAM2

Related Sequences

BC028919 AAH28919 Q6PIT9
BC038957 AAH38957 Q14106
D64109 BAA10971 Q14106
AB035207 BAA87042 Q14106
AB051450 BAB33333 Q14106
CR456594 CAG30480 Q14106
CR541684 CAG46485 Q14106
CU013194 CAK54625  
CU013482 CAK54924  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens TOB2 NP_057356 R.norvegicus Tob2 315159   NP_001007147 92
M.musculus Tob2 57259 Gene Info NP_065253 90
D.melanogaster Tob 32574   NP_001162772 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta