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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SERPIND1, serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Sequence ID:NM_000185
RefSeqGene ID:NG_012076
Entrez Gene ID:3053
Ensembl ID:ENSG00000099937

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
THROMBOPHILIA DUE TO HEPARIN COFACTOR II DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q11.21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 21128400 - 21141933

NM_000185 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1512112838221128432
529562113358421134488
95712302113825921138532
123113752114029121140435
137622212114116221142007

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5262187Full LengthBC035028serpin peptidase inhibitor, clade D (heparin cofactor), member 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000176  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000185 NP_000176 P05546 Serpin

Related Sequences

 
mRNAGenPeptSwissProt
M12849 AAA52642 P05546
BC035028 AAH35028 Q8IVC0
DQ891203 ABM82129  
DQ894386 ABM85312  
AK314200 BAG36878 P05546
X03498 CAA27218 P05546
CR456573 CAG30459 P05546
CU013172 CAK54603  
CU013460 CAK54902  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SERPIND1 NP_000176 R.norvegicus Serpind1 79224   NP_077358 86
M.musculus Serpind1 15160 Gene Info NP_032249 86

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)