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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. STK4, serine/threonine kinase 4
Sequence ID:NM_006282
RefSeqGene ID:NG_032172
Entrez Gene ID:6789
Ensembl ID:ENSG00000101109

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
T-CELL IMMUNODEFICIENCY, RECURRENT INFECTIONS, AUTOIMMUNITY,AND CARDIAC MALFORMATIONS 

Cytogenetic Location (from UniGene)

Cytogenetic Location:20q11.2-q13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 43595135 - 43708599

 Exon Info From UCSC:
NM_006282

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7939613Full LengthBC093768serine/threonine kinase 4
4390245IncompleteBC058916serine/threonine kinase 4
4400771IncompleteBC015332serine/threonine kinase 4
5269433IncompleteBC042861serine/threonine kinase 4
5301283IncompleteBC029511serine/threonine kinase 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006273  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_006282 NP_006273 Q13043 EC 2.7.11.1 Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U18297 AAA83254 Q13043 EC 2.7.11.1
U60207 AAB17262 Q13043 EC 2.7.11.1
BC005231 AAH05231 Q9BS84  
BC015332 AAH15332 A0PJ51  
BC029511 AAH29511 Q13043 EC 2.7.11.1
BC058916 AAH58916 Q13043 EC 2.7.11.1
BC093768 AAH93768 Q13043 EC 2.7.11.1
AB209315 BAD92552 Q59FZ4  
AK315238 BAG37665 Q13043 EC 2.7.11.1
Z25430 CAA80917 Q15452  
CR933633 CAI45939 Q5H9T5  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens STK4 NP_006273 M.musculus Stk4 58231 Gene Info NP_067395 97
R.norvegicus Stk4 311622   NP_001101270 96
A.thaliana SIK1 843253   NP_849865 45

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)