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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. BMPR2, Bone morphogenetic protein receptor, type II (serine/threonine kinase)
Sequence ID:NM_001204
RefSeqGene ID:NG_009363
Entrez Gene ID:659
Ensembl ID:ENSG00000204217

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, stem cell, stomach, synovium, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q33-q34Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 203426998 - 203429771

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6149698Full LengthBC052985bone morphogenetic protein receptor, type II (serine/threonine kinase)
3924242IncompleteBC032011bone morphogenetic protein receptor, type II (serine/threonine kinase)
5261941IncompleteBC035097bone morphogenetic protein receptor, type II (serine/threonine kinase)
5277612IncompleteBC043650bone morphogenetic protein receptor, type II (serine/threonine kinase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001195  

Protein Infomation

NM_001204 NP_001195 Q13873 EC Pkinase

Related Sequences

U20165 AAC50105 Q13873 EC
BC052985 AAH52985 Q13873 EC
AY277593 AAQ18032 Q597H5  
D50516 BAA09094 Q13873 EC
AK292430 BAF85119 A8K8R5  
Z48923 CAA88759 Q13873 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens BMPR2 NP_001195 M.musculus Bmpr2 12168 Gene Info NP_031587 97
R.norvegicus Bmpr2 140590   NP_536332 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta