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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. AK2, Adenylate kinase 2
Sequence ID:NM_013411
NM_001199199
NM_001625
RefSeqGene ID:NG_016269
Entrez Gene ID:204
Ensembl ID:ENSG00000004455

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
RETICULAR DYSGENESIS 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p34Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 33478643 - 33502467

 Exon Info From UCSC:
NM_013411
NM_001625

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4304794Full LengthBC009405adenylate kinase 2
6471696Full LengthBC090040adenylate kinase 2
6663039Full LengthBC070127adenylate kinase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001616  NP_037543  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001199199 NP_001186128      
NM_001625 NP_001616 P54819 EC 2.7.4.3 ADK
ADK_lid
NM_013411 NP_037543     ADK
ADK_lid

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U84371 AAB41790 P54819 EC 2.7.4.3
U54645 AAC13881 P54819 EC 2.7.4.3
U39945 AAC52061 P54819 EC 2.7.4.3
BC009405 AAH09405 P54819 EC 2.7.4.3
BC070127 AAH70127 P54819 EC 2.7.4.3
BC090040 AAH90040 P54819 EC 2.7.4.3
AY080899 AAL87027 P54819 EC 2.7.4.3
AY080900 AAL87028 P54819 EC 2.7.4.3
AB005621 BAC16747 P54819 EC 2.7.4.3
AB005622 BAC16748 P54819 EC 2.7.4.3
AK291676 BAF84365 P54819 EC 2.7.4.3
AK295105 BAG58139 P54819 EC 2.7.4.3
AK296863 BAG59426 P54819 EC 2.7.4.3
AK297036 BAG59564 B4DLK2  
AB451267 BAG70081 P54819 EC 2.7.4.3
AB451394 BAG70208 P54819 EC 2.7.4.3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AK2 NP_001616 M.musculus Ak2 11637 Gene Info NP_001029138 95
R.norvegicus Ak2 24184   NP_112248 93
A.gambiae KAD2_ANOGA 1269521   XP_308155 67
D.melanogaster Adk2 37834   NP_523836 66
C.elegans let-754 176118   NP_498730 63
N.crassa NCU01550 3872391   XP_956253 59
S.pombe adk1 2542704   NP_593685 59
S.cerevisiae ADK1 851812   NP_010512 58
A.thaliana AT5G50370 835104   NP_199848 55
A.thaliana ADK1 836459   NP_201145 53
P.falciparum PF10_0086 810244   XP_001347371 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)