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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. RAPGEF4, Rap guanine nucleotide exchange factor (GEF) 4
Sequence ID:NM_001100397
Entrez Gene ID:11069
Ensembl ID:ENSG00000091428

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q31-q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 173600654 - 173916544

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4801092Full LengthBC040183Rap guanine nucleotide exchange factor (GEF) 4
4823935Full LengthBC024004Rap guanine nucleotide exchange factor (GEF) 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_008954  

Protein Infomation

NM_001100397 NP_001093867    
NM_007023 NP_008954 Q8WZA2 cNMP_binding

Related Sequences

U78516 AAD03422 Q8WZA2
BC024004 AAH24004 Q8WZA2
BC040183 AAH40183 Q8WZA2
DQ894011 ABM84937  
DQ890549 ABM92166  
AB027471 BAB72179 Q8WZA2
AB209681 BAD92918 Q59EY0
AB075513 BAE45759 Q3LIA9
AK313084 BAG35910 Q8WZA2
AK294433 BAH11764 B7Z278
AK294445 BAH11769 B7Z283
AK294914 BAH11923 B7Z278
AK294997 BAH11944 B7Z2Q8
AK295002 BAH11946 B7Z2R0
AK296340 BAH12322 B7Z3T6
AK302732 BAH13791 B7Z805
AK304278 BAH14148 Q8WZA2
AK316014 BAH14385 B7Z9P9
AK316072 BAH14443 B7Z283

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens RAPGEF4 NP_008954 M.musculus Rapgef4 56508 Gene Info NP_062662 97
R.norvegicus Rapgef4 252857   XP_215985 97
A.gambiae AgaP_AGAP007307 1269861   XP_308514 53
D.melanogaster Epac 35588   NP_001097202 51
C.elegans epac-1 176432   NP_499256 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)