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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PDK1, pyruvate dehydrogenase kinase, isozyme 1
Sequence ID:NM_002610
Entrez Gene ID:5163
Ensembl ID:ENSG00000152256

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:2q31.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 173461458 - 173463512

 Exon Info From UCSC:
NM_002610

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4778360Full LengthBC039158pyruvate dehydrogenase kinase, isozyme 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002601  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002610 NP_002601 Q15118 EC 2.7.11.2 HATPase_c

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L42450 AAC42009 Q15118 EC 2.7.11.2
BC039158 AAH39158 Q15118 EC 2.7.11.2
DQ234350 ABB29979 Q308M4  
DQ891300 ABM82226    
DQ893348 ABM84274    
DQ894484 ABM85410    
DQ896668 ABM87667    
AK312700 BAG35578 Q15118 EC 2.7.11.2
AK294194 BAH11693 B7Z207  
AK302321 BAH13672 B7Z7N6  
AK304388 BAH14173 B7Z937  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PDK1 NP_002601 R.norvegicus Pdk1 116551   NP_446278 93
M.musculus Pdk1 228026 Gene Info NP_766253 92
N.crassa NCU06760 3879656   XP_963532 45
A.thaliana PDK 819826   NP_187300 44
S.pombe SPAC644.11c 2543651   NP_593879 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)