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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. LCK, lymphocyte-specific protein tyrosine kinase
Sequence ID:NM_001042771
NM_005356
RefSeqGene ID:NG_023387
Entrez Gene ID:3932
Ensembl ID:ENSG00000182866

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:1p34.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 32739969 - 32751317

 Exon Info From UCSC:
NM_001042771
NM_005356

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4341278Full LengthBC013200lymphocyte-specific protein tyrosine kinase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005347  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001042771 NP_001036236      
NM_005356 NP_005347 P06239 EC 2.7.10.2 SH2
SH3_1
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U07236 AAA18225 P06239 EC 2.7.10.2
M36881 AAA59502 P06239 EC 2.7.10.2
AF228313 AAF34794 P06239 EC 2.7.10.2
BC013200 AAH13200 P06239 EC 2.7.10.2
DQ891675 ABM82601    
DQ894861 ABM85787    
AK098027 BAG53565 B3KUV3  
AK303073 BAG64189 B4DZS7  
X04476 CAA28165 P06239 EC 2.7.10.2
X05027 CAA28691 P06239 EC 2.7.10.2
X06369 CAA29667 P06239 EC 2.7.10.2
X13529 CAA31884 P06239 EC 2.7.10.2
AJ865079 CAI23831 Q573B4  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LCK NP_005347 M.musculus Lck 16818 Gene Info NP_001155905 97
R.norvegicus Lck 313050   NP_001094179 97

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta