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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ARHGEF4, Rho guanine nucleotide exchange factor (GEF) 4
Sequence ID:NM_015320
NM_032995
Entrez Gene ID:50649
Ensembl ID:ENSG00000136002

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:2q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 131675003 - 131804824

 Exon Info From UCSC:
NM_015320
NM_032995

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100064221Full LengthBC160189Rho guanine nucleotide exchange factor (GEF) 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_127462  NP_056135  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_015320 NP_056135 Q9NR80 SH3_1
PH
RhoGEF
SH3_2
NM_032995 NP_127462   SH3_1
PH
RhoGEF
SH3_2

Related Sequences

 
mRNAGenPeptSwissProt
AF249745 AAF79955 Q9NR80
BC139742 AAI39743 A4QPB6
BC160189 AAI60189  
DQ424905 ABD83670 Q1ZYL3
AB029035 BAA83064 Q9NR80
AB042199 BAB11941 Q9NR80
AL137289 CAB70681 Q9NTG0

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ARHGEF4 NP_056135 M.musculus Arhgef4 226970 Gene Info NP_898840 93
R.norvegicus Arhgef4 301334   XP_237049 85

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)