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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ERCC3, excision repair cross-complementing rodent repair deficiency, complementation group 3
Sequence ID:NM_000122
RefSeqGene ID:NG_007454
Entrez Gene ID:2071
Ensembl ID:ENSG00000163161

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
TRICHOTHIODYSTROPHYERCC2
GTF2H5
XERODERMA PIGMENTOSUM, GROUP B 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 128014865 - 128051657

 Exon Info From UCSC:
NM_000122

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3958781Full LengthBC008820excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000113  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000122 NP_000113 P19447 EC 3.6.4.12 Helicase_C
ResIII

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M31899 AAA52396 P19447 EC 3.6.4.12
BC008820 AAH08820 P19447 EC 3.6.4.12
DQ893802 ABM84728    
EU176179 ABW03630    
AK222465 BAD96185 Q53HW5  
AK290474 BAF83163 A8K359  
AK091500 BAG52374 B3KRG2  
AK095557 BAG53083 B3KTH1  
AK300250 BAG62016 B4DTK4  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ERCC3 NP_000113 M.musculus Ercc3 13872 Gene Info NP_598419 96
R.norvegicus Ercc3 291703   NP_001026814 96
A.gambiae AgaP_AGAP012169 1280516   XP_320364 71
D.melanogaster hay 39202   NP_524020 71
C.elegans Y66D12A.15 176584   NP_499487 67
S.cerevisiae SSL2 854663   NP_012123 59
A.thaliana XPB1 834139   NP_568592 58
A.thaliana XPB2 834138   NP_568591 58
S.pombe ptr8 2542174   NP_593474 57
N.crassa NCU06438 3873498   XP_957329 54

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)