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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. POLE4, polymerase (DNA-directed), epsilon 4, accessory subunit
Sequence ID:NM_019896
Entrez Gene ID:56655
Ensembl ID:ENSG00000115350

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, brain, cerebrum, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, pancreas, pancreatic islet, pituitary gland, placenta, pooled tissue, prostate, retina, skin, stem cell, t-cell, testis, uncharacterized tissue, uterus
  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 75186481 - 75252014

NM_019896 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
12457518577475186018
2463307518646775186551
3313727518723175187272
3736957519653575196857

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5443810Full LengthBC031331polymerase (DNA-directed), epsilon 4 (p12 subunit)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_063949  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_019896 NP_063949 Q9NR33 EC 2.7.7.7 CBFD_NFYB_HMF

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC031331 AAH31331 Q9NR33 EC 2.7.7.7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens POLE4 NP_063949 M.musculus Pole4 66979 Gene Info NP_080158 96
R.norvegicus Pole4 362385   NP_001102104 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)