Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. IAPP, islet amyloid polypeptide
Sequence ID:NM_000415
Entrez Gene ID:3375
Ensembl ID:ENSG00000121351

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:12p12.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 21526285 - 21531360

NM_000415 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11372152580121525937
1382322152627021526364
23319752153117021532912

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40080837BC111849islet amyloid polypeptide

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000406  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000415 NP_000406 P10997 Calc_CGRP_IAPP

Related Sequences

 
mRNAGenPeptSwissProt
J04422 AAA52281 P10997
BC111849 AAI11850  
DQ516082 ABG27010 P10997
X14904 CAA33032 P10997
X14905 CAA33033 P10997

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IAPP NP_000406 M.musculus Iapp 15874 Gene Info NP_034621 69
R.norvegicus Iapp 24476   NP_036718 68

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)