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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. KPNA4, karyopherin alpha 4 (importin alpha 3)
Sequence ID:NM_002268
Entrez Gene ID:3840
Ensembl ID:ENSG00000186432

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q25.33Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 160219781 - 160283073

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4821602Full LengthBC034493karyopherin alpha 4 (importin alpha 3)
4838709Full LengthBC028691karyopherin alpha 4 (importin alpha 3)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002259  

Protein Infomation

NM_002268 NP_002259 O00629 Arm

Related Sequences

U93240 AAC25605 O00629
BC007458 AAH07458 Q96IJ5
BC016754 AAH16754 Q96KW7
BC028691 AAH28691 O00629
BC034493 AAH34493 O00629
DQ890866 ABM81792  
DQ894021 ABM84947  
AB002533 BAA19546 O00629
AK291041 BAF83730 O00629
Y12393 CAA73025 O00629

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens KPNA4 NP_002259 M.musculus Kpna4 16649 Gene Info NP_032493 99
R.norvegicus Kpna4 361959   NP_001014793 99
A.gambiae AgaP_AGAP001273 1281905   XP_321878 71
D.melanogaster Kap-alpha3 41158   NP_001163572 68
C.elegans ima-3 177533   NP_501227 66

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)