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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ODC1, ornithine decarboxylase 1
Sequence ID:NM_002539
RefSeqGene ID:NG_012105
Entrez Gene ID:4953
Ensembl ID:ENSG00000115758

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
COLON CANCERAKT1
APC
APC
AURKA
AXIN2
BCL10
BUB1B
CCND1
EP300
FGFR3
FLCN
MLH3
NRAS
PDGFRL
PIK3CA
PIK3CA
PLA2G2A
PTPRJ
SMAD7
TLR2
TLR4
TP53
TP53

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p25Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 10580726 - 10587906

 Exon Info From UCSC:
NM_002539

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5088190Full LengthBC025296ornithine decarboxylase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002530  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002539 NP_002530 P11926 EC 4.1.1.17 Orn_DAP_Arg_deC
Orn_Arg_deC_N

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M16650 AAA59966 P11926 EC 4.1.1.17
M20372 AAA59968 P11926 EC 4.1.1.17
BC025296 AAH25296 P11926 EC 4.1.1.17
DQ185043 ABD14423 Q2F835  
DQ896069 ABM87068    
EU176390 ABW03841    
EU831702 ACE86536    
EU831615 ACE87215    
D28365 BAA05731    
AK292352 BAF85041 P11926 EC 4.1.1.17
AK312766 BAG35632 P11926 EC 4.1.1.17
AK301956 BAG63370 B4DXF8  
X53271 CAA37369 P11926 EC 4.1.1.17
X55362 CAA39047 P11926 EC 4.1.1.17

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ODC1 NP_002530 R.norvegicus Odc1 24609   NP_036747 92
M.musculus Odc1 18263 Gene Info NP_038642 91
S.pombe spe1 2542855   NP_594665 55
N.crassa NCU01271 3876899   XP_960749 51
A.gambiae AgaP_AGAP011805 1280843   XP_320710 50
S.cerevisiae SPE1 853651   NP_012737 50
D.melanogaster Odc1 35766   NP_477052 49
C.elegans odc-1 179079   NP_504752 48
D.melanogaster Odc2 35767   NP_477053 42
P.falciparum PF10_0322 810479   XP_001347606 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)