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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. TPO, thyroid peroxidase
Sequence ID:NM_000547
NM_001206744
NM_001206745
NM_175719
NM_175721
NM_175722
NM_175720
RefSeqGene ID:NG_011581
Entrez Gene ID:7173
Ensembl ID:ENSG00000115705

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
THYROID DYSHORMONOGENESIS 2A 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p25Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 1418180 - 1546246

 Exon Info From UCSC:
NM_000547
NM_175719
NM_175721
NM_175722

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30329791Full LengthBC095448thyroid peroxidase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_783653  NP_000538  NP_783650  NP_783652  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000547 NP_000538 P07202 EC 1.11.1.8 EGF
Sushi
An_peroxidase
EGF_CA
NM_001206744 NP_001193673      
NM_001206745 NP_001193674      
NM_175719 NP_783650     EGF
Sushi
An_peroxidase
EGF_CA
NM_175721 NP_783652     Sushi
An_peroxidase
NM_175722 NP_783653     EGF
Sushi
An_peroxidase
EGF_CA

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
J02969 AAA61215 P07202 EC 1.11.1.8
J02970 AAA61216 P07202 EC 1.11.1.8
M17755 AAA61217 P07202 EC 1.11.1.8
M55702 AAA61218 P07202 EC 1.11.1.8
M55702 AAA61219 P07202 EC 1.11.1.8
BC063107 AAH63107 Q6P534  
BC095448 AAH95448 Q502Y3  
AF439430 AAL74416 P07202 EC 1.11.1.8
AF533528 AAN04471 P07202 EC 1.11.1.8
AF533529 AAN04472 P07202 EC 1.11.1.8
AF533530 AAN04473 P07202 EC 1.11.1.8
AF533531 AAN04474 P07202 EC 1.11.1.8
AY136822 AAN11302 P07202 EC 1.11.1.8
AB208960 BAD92197 Q59GZ9  
X17358 CAA35235 P07202 EC 1.11.1.8
Y00406 CAA68467 P07202 EC 1.11.1.8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TPO NP_000538 R.norvegicus Tpo 54314   NP_062226 76
M.musculus Tpo 22018 Gene Info NP_033443 75

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)