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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PPP2R1A, protein phosphatase 2, regulatory subunit A, alpha
Sequence ID:NM_014225
NR_033500
Entrez Gene ID:5518
Ensembl ID:ENSG00000105568

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.41Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 52704345 - 52729670

 Exon Info From UCSC:
NM_014225

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2987938Full LengthBC001537protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_055040  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_014225 NP_055040 P30153 HEAT

Related Sequences

 
mRNAGenPeptSwissProt
J02902 AAA36399 P30153
BC001537 AAH01537 P30153
BT008074 AAP36766  
DQ892756 ABM83682  
DQ896000 ABM86978  
AK091387 BAC03652 Q8NB89
AK290593 BAF83282 A8K3H8
AK291932 BAF84621 A8K7B7
AK315700 BAG38062 A8K7B7
AK090488 BAG52168 B3KQV6
AK293174 BAG56718 B4DDF7
AK293493 BAG56980 B4DE69
AK299012 BAG61093 B4DQY1
AK303934 BAG64862 B4E1Q0
CR450340 CAG29336 P30153

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PPP2R1A NP_055040 M.musculus Ppp2r1a 51792 Gene Info NP_058587 100
R.norvegicus Ppp2r1a 117281   NP_476481 100
D.melanogaster Pp2A-29B 2768940   NP_001027226 75
A.gambiae AgaP_AGAP009105 1280057   XP_319856 72
C.elegans paa-1 175750   NP_498162 63
A.thaliana PP2AA3 837892   NP_172790 59
A.thaliana PP2AA2 822171   NP_189208 59
N.crassa NCU00488 5847903   XP_001728513 56
S.pombe paa1 2543042   NP_594948 54
S.cerevisiae TPD3 851217   NP_009386 46

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)