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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MAP3K10, mitogen-activated protein kinase kinase kinase 10
Sequence ID:NM_002446
Entrez Gene ID:4294
Ensembl ID:ENSG00000130758

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 40697650 - 40721480

NM_002446 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
19704069765040698619
97111514070428140704461
115213004071039140710539
130114764071102740711202
147717234071181740712063
172418404071500940715125
184120124071871140718882
201321254071898240719094
212628304071942340720127
283134354072087640721480

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40080650BC111460mitogen-activated protein kinase kinase kinase 10

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002437  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002446 NP_002437 Q02779 EC 2.7.11.25 SH3_1
Pkinase
SH3_2
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC111460 AAI11461 Q02779 EC 2.7.11.25
X90846 CAA62351 Q02779 EC 2.7.11.25
Z48615 CAA88531 Q02779 EC 2.7.11.25

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MAP3K10 NP_002437 M.musculus Map3k10 269881 Gene Info NP_001074761 94
R.norvegicus Map3k10 308463   XP_218368 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta