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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GPI, glucose-6-phosphate isomerase
Sequence ID:NM_000175
NM_001184722
RefSeqGene ID:NG_012838
Entrez Gene ID:2821
Ensembl ID:ENSG00000105220

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
HEMOLYTIC ANEMIA, NONSPHEROCYTIC, DUE TO GLUCOSE PHOSPHATE ISOMERASEDEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 34855885 - 34891232

 Exon Info From UCSC:
NM_000175
NM_001184722

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2906270Full LengthBC004982glucose phosphate isomerase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000166  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000175 NP_000166 P06744 EC 5.3.1.9 PGI
NM_001184722 NP_001171651      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
K03515 AAA36368 P06744 EC 5.3.1.9
BC004982 AAH04982 P06744 EC 5.3.1.9
DQ892924 ABM83850    
DQ896173 ABM87172    
AB209575 BAD92812 Q59F85  
AK293446 BAG56947 B4DE36  
AK294396 BAG57650 P06744 EC 5.3.1.9
AK301103 BAG62702 B4DVJ0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GPI NP_000166 M.musculus Gpi1 14751 Gene Info NP_032181 89
R.norvegicus Gpi 292804   NP_997475 88
D.melanogaster Pgi 35886   NP_724724 69
A.gambiae AgaP_AGAP012167 1280518   XP_320366 68
C.elegans gpi-1 173227   NP_001021837 68
S.pombe pgi1 2539625   NP_596635 60
S.cerevisiae PGI1 852495   NP_009755 59
N.crassa NCU07281 3878284   XP_962135 59

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta