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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PKN1, protein kinase N1
Sequence ID:NM_002741
Entrez Gene ID:5585
Ensembl ID:ENSG00000123143

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 14551071 - 14582678

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5752583Full LengthBC040061protein kinase N1
30342125Full LengthBC094766protein kinase N1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002732  NP_998725  

Protein Infomation

NM_002741 NP_002732 Q16512 EC Pkinase
NM_213560 NP_998725     Pkinase

Related Sequences

S75546 AAB33345 Q16512 EC
U33053 AAC50209 Q16512 EC
BC040061 AAH40061 Q16512 EC
BC094766 AAH94766 Q16512 EC
DQ892477 ABM83403    
D26181 BAA05169 Q16512 EC
AK292130 BAF84819 Q16512 EC
AK313886 BAG36611 Q16512 EC
AK123007 BAG53845 Q16512 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PKN1 NP_998725 M.musculus Pkn1 320795 Gene Info NP_796236 92
R.norvegicus Pkn1 29355   NP_058871 92

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta