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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. KEAP1, kelch-like ECH-associated protein 1
Sequence ID:NM_012289
Entrez Gene ID:9817
Ensembl ID:ENSG00000079999

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 10596801 - 10613437

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3163902Full LengthBC002417kelch-like ECH-associated protein 1
3910857Full LengthBC015945kelch-like ECH-associated protein 1
3955118Full LengthBC002930kelch-like ECH-associated protein 1
2906137IncompleteBC021957kelch-like ECH-associated protein 1
4549407IncompleteBC014118kelch-like ECH-associated protein 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_036421  NP_987096  

Protein Infomation

NM_012289 NP_036421 Q14145 BTB
NM_203500 NP_987096   BTB

Related Sequences

BC002417 AAH02417 Q14145
BC002930 AAH02930 Q14145
BC015945 AAH15945 Q14145
BC021957 AAH21957 Q14145
AF361886 AAK51082 Q14145
DQ893639 ABM84565  
DQ895597 ABM86523  
EU176209 ABW03660  
D50922 BAA09481 Q14145
AK056204 BAG51647 Q14145

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens KEAP1 NP_987096 R.norvegicus Keap1 117519   NP_476493 94
M.musculus Keap1 50868 Gene Info NP_001103775 94
A.gambiae AgaP_AGAP003645 1274312   XP_562507 51
D.melanogaster Keap1 42062   NP_732202 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta