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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PIN1, peptidylprolyl cis/trans isomerase, NIMA-interacting 1
Sequence ID:NM_006221
NR_038422
NR_038830
RefSeqGene ID:NG_029167
Entrez Gene ID:5300
Ensembl ID:ENSG00000127445

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, t-cell, testis, thymus, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 9946015 - 9960358

NM_006221 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
18099459989946077
8129399491119949323
29440499587059958815
40599799597659960357

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3941595Full LengthBC002899peptidylprolyl cis/trans isomerase, NIMA-interacting 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006212  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_006221 NP_006212 Q13526 EC 5.2.1.8 WW
Rotamase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U49070 AAC50492 Q13526 EC 5.2.1.8
BC002899 AAH02899 Q13526 EC 5.2.1.8
BC031971 AAH31971 Q49AR7  
BT019331 AAV38138 Q13526 EC 5.2.1.8
DQ892978 ABM83904    
DQ896226 ABM87225    
AK291074 BAF83763 Q13526 EC 5.2.1.8
AK097558 BAG53486 B3KUM4  
CR407654 CAG28582 Q13526 EC 5.2.1.8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PIN1 NP_006212 R.norvegicus Pin1 298696   NP_001100171 97
M.musculus Pin1 23988 Gene Info NP_075860 96
C.elegans Y110A2AL.13 190941   NP_494393 60
A.gambiae AgaP_AGAP004321 1274464   XP_313593 58
D.melanogaster dod 33111   NP_523428 58
N.crassa NCU08554 3879175   XP_963036 57
A.thaliana PIN1AT 816316   NP_179395 53
S.pombe pin1 2539218   NP_587913 52
S.cerevisiae ESS1 853475   NP_012551 47

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta