Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PHLPP1, PH domain and leucine rich repeat protein phosphatase 1
Sequence ID:NM_194449
RefSeqGene ID:NG_031923
Entrez Gene ID:23239
Ensembl ID:ENSG00000081913

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:18q21.33Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:18: 60383958 - 60647665

 Exon Info From UCSC:
NM_194449

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3916044Full LengthBC014927PH domain and leucine rich repeat protein phosphatase
8991993Full LengthBC126277PH domain and leucine rich repeat protein phosphatase
3874711IncompleteBC010706PH domain and leucine rich repeat protein phosphatase
4341956IncompleteBC063519PH domain and leucine rich repeat protein phosphatase
4641238IncompleteBC082244PH domain and leucine rich repeat protein phosphatase
5259974IncompleteBC047653PH domain and leucine rich repeat protein phosphatase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_919431  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_194449 NP_919431 O60346 EC 3.1.3.16 PH
PP2C
LRR_1

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF130097 AAG35522 Q9H380  
BC010706 AAH10706 O60346 EC 3.1.3.16
BC014927 AAH14927 O60346 EC 3.1.3.16
BC047653 AAH47653 O60346 EC 3.1.3.16
BC063519 AAH63519 O60346 EC 3.1.3.16
BC082244 AAH82244 O60346 EC 3.1.3.16
BC126277 AAI26278 O60346 EC 3.1.3.16
AB011178 BAA25532 O60346 EC 3.1.3.16
AK001924 BAA91980 O60346 EC 3.1.3.16

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PHLPP1 NP_919431 M.musculus Phlpp1 98432 Gene Info NP_598582 90
R.norvegicus Phlpp1 59265   NP_067689 89

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)