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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SMAD7, SMAD family member 7
Sequence ID:NM_001190821
NM_001190822
NM_001190823
NM_005904
RefSeqGene ID:NG_023330
Entrez Gene ID:4092
Ensembl ID:ENSG00000101665

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
COLON CANCERAKT1
APC
APC
AURKA
AXIN2
BCL10
BUB1B
CCND1
EP300
FGFR3
FLCN
MLH3
NRAS
ODC1
PDGFRL
PIK3CA
PIK3CA
PLA2G2A
PTPRJ
TLR2
TLR4
TP53
TP53
COLORECTAL CANCER 

Cytogenetic Location (from UniGene)

Cytogenetic Location:18q21.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:18: 46446222 - 46477081

 Exon Info From UCSC:
NM_001190821
NM_001190822
NM_001190823
NM_005904

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30915321Full LengthBC074818SMAD family member 7
30915535Full LengthBC074819SMAD family member 7

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005895  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001190821 NP_001177750    
NM_001190822 NP_001177751    
NM_001190823 NP_001177752    
NM_005904 NP_005895 O15105 MH1
MH2

Related Sequences

 
mRNAGenPeptSwissProt
AF010193 AAB81246 O15105
AF015261 AAB81354 O15105
BC074818 AAH74818 O15105
BC074819 AAH74819 O15105
AK131394 BAG54770 B3KYA8
AK301535 BAH13509 B7Z773

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SMAD7 NP_005895 M.musculus Smad7 17131 Gene Info NP_001036125 98
R.norvegicus Smad7 81516   NP_110485 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta