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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PIK3C3, phosphatidylinositol 3-kinase, catalytic subunit type 3
Sequence ID:NM_002647
Entrez Gene ID:5289
Ensembl ID:ENSG00000078142

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:18q12.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:18: 39617713 - 39631276

 Exon Info From UCSC:
NM_002647

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4823337Full LengthBC033004phosphoinositide-3-kinase, class 3
5517878Full LengthBC053651phosphoinositide-3-kinase, class 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002638  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002647 NP_002638 Q8NEB9 EC 2.7.1.137 PI3_PI4_kinase
PI3Ka
PI3K_C2

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC033004 AAH33004 Q8NEB9 EC 2.7.1.137
BC053651 AAH53651 Q8NEB9 EC 2.7.1.137
DQ893712 ABM84638    
DQ890552 ABM92169    
AK298517 BAG60721 B4DPV9  
Z46973 CAA87094 Q8NEB9 EC 2.7.1.137

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PIK3C3 NP_002638 R.norvegicus Pik3c3 65052   NP_075247 98
M.musculus Pik3c3 225326 Gene Info NP_852079 98
D.melanogaster Pi3K59F 37733   NP_477133 59
A.gambiae AgaP_AGAP010273 1279696   XP_319464 57
S.pombe pik3 2543444   NP_594699 47
A.thaliana VPS34 842344   NP_176251 46
C.elegans vps-34 172280   NP_491741 42
N.crassa NCU00656 3881921   XP_965796 41
S.cerevisiae VPS34 850941   NP_013341 40

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)