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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. P4HB, prolyl 4-hydroxylase, beta polypeptide
Sequence ID:NM_000918
Entrez Gene ID:5034
Ensembl ID:ENSG00000185624

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q25Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 79801042 - 79803107

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3848651Full LengthBC029617prolyl 4-hydroxylase, beta polypeptide
3879411Full LengthBC010859prolyl 4-hydroxylase, beta polypeptide
5443660Full LengthBC071892prolyl 4-hydroxylase, beta polypeptide
4861217IncompleteBC014504prolyl 4-hydroxylase, beta polypeptide

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000909  

Protein Infomation

NM_000918 NP_000909 P07237 EC Thioredoxin

Related Sequences

J02783 AAA61169 P07237 EC
BC010859 AAH10859 P07237 EC
BC014504 AAH14504 Q96C96  
BC029617 AAH29617 P07237 EC
BC071892 AAH71892 P07237 EC
JF432204 ADZ15421    
AB062434 BAB93497 Q8NI86  
AK315631 BAG37999 P07237 EC
AK095938 BAG53171 B3KTQ9  
AK128783 BAG54732 B3KTQ9  
AK296206 BAG58932 B4DJS0  
AK297081 BAG59598 B4DLN6  
AK297967 BAG60277 B4DNL5  
AK298005 BAG60311 B4DNP9  
AK300561 BAG62267 B4DUA5  
X05130 CAA28775 P07237 EC
X07077 CAA30112 P07237 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens P4HB NP_000909 R.norvegicus P4hb 25506   NP_037130 94
M.musculus P4hb 18453 Gene Info NP_035162 94
C.elegans pdi-2 180724   NP_508778 59
A.gambiae AgaP_AGAP012407 1280308   XP_551775 56
D.melanogaster Pdi 39651   NP_524079 56
A.thaliana PDIL1-4 836185   NP_851234 41
A.thaliana PDIL1-3 824661   NP_191056 40
S.pombe SPAC1F5.02 2541460   NP_592871 37
N.crassa NCU09223 3875289   XP_959167 36
S.cerevisiae PDI1 850314   NP_009887 34

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta