Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MAP2K6, Mitogen-activated protein kinase kinase 6
Sequence ID:NM_002758
RefSeqGene ID:NG_029437
Entrez Gene ID:5608
Ensembl ID:ENSG00000108984

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:17q24.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 67501920 - 67537894

 Exon Info From UCSC:
NM_002758

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4499772Full LengthBC012009mitogen-activated protein kinase kinase 6

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002749  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002758 NP_002749 P52564 EC 2.7.12.2 Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U39065 AAB03705 P52564 EC 2.7.12.2
U39064 AAB03708 P52564 EC 2.7.12.2
U49732 AAB05035 P52564 EC 2.7.12.2
U39656 AAC50388 P52564 EC 2.7.12.2
U39657 AAC50389 P52564 EC 2.7.12.2
BC012009 AAH12009 P52564 EC 2.7.12.2
DQ891488 ABM82414    
DQ894673 ABM85599    
D87905 BAA13496 P52564 EC 2.7.12.2
AK290747 BAF83436 A8K3Y2  
AB451252 BAG70066 B5BU16  
AB451376 BAG70190 A8K3Y2  
X96757 CAA65532 P52564 EC 2.7.12.2
BX641121 CAE46056 Q6MZH7  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MAP2K6 NP_002749 M.musculus Map2k6 26399 Gene Info NP_036073 98
R.norvegicus Map2k6 114495   NP_446155 97
C.elegans sek-1 181043   NP_509322 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta