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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. RPS6KB1, Ribosomal protein S6 kinase, 70kDa, polypeptide 1
Sequence ID:NM_003161
RefSeqGene ID:NG_029513
Entrez Gene ID:6198
Ensembl ID:ENSG00000108443

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q23.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 58025760 - 58027781

 Exon Info From UCSC:
NM_003161

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6142009Full LengthBC053365ribosomal protein S6 kinase, 70kDa, polypeptide 1
4799942IncompleteBC030763ribosomal protein S6 kinase, 70kDa, polypeptide 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003152  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_003161 NP_003152 P23443 EC 2.7.11.1 Pkinase
Pkinase_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M60724 AAA36410 P23443 EC 2.7.11.1
M60725 AAA36411 P23443 EC 2.7.11.1
BC036033 AAH36033 Q4G0X7  
BC053365 AAH53365 Q7Z721  
AK312875 BAG35726 B2R779  
AK293247 BAG56781 B4DDM0  
AK297147 BAG59646 B4DLT4  
AK300202 BAG61973 B4DTG1  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens RPS6KB1 NP_003152 M.musculus Rps6kb1 72508 Gene Info NP_001107806 99
R.norvegicus Rps6kb1 83840   NP_114191 99
D.melanogaster S6k 38654   NP_523941 73
A.gambiae AgaP_AGAP007333 1269844   XP_308496 67
C.elegans rsks-1 176554   NP_499447 63

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta