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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. NME2, NME/NM23 nucleoside diphosphate kinase 2
Sequence ID:NM_001018137
NM_001018138
NM_001018139
NM_001198682
NM_002512
Entrez Gene ID:4831
Ensembl ID:ENSG00000011052

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, adrenal medulla, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 49230936 - 49239422

 Exon Info From UCSC:
NM_001018137
NM_001018138
NM_001018139
NM_002512

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3349768Full LengthBC002476non-metastatic cells 2, protein (NM23B) expressed in
30524221Full LengthBC095458non-metastatic cells 2, protein (NM23B) expressed in

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000260  NP_001018146  NP_002503  NP_001018149  NP_001018148  NP_937818  NP_001018147  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000269 NP_000260 P15531 EC 2.7.4.6 NDK
NM_001018136 NP_001018146     NDK
NM_001018137 NP_001018147 Q6FHN3
P22392
EC 2.7.13.3
EC 2.7.4.6
NDK
NM_001018138 NP_001018148 Q6FHN3
P22392
EC 2.7.13.3
EC 2.7.4.6
NDK
NM_001018139 NP_001018149 Q6FHN3
P22392
EC 2.7.13.3
EC 2.7.4.6
NDK
NM_001198682 NP_001185611      
NM_002512 NP_002503 Q6FHN3
P22392
EC 2.7.13.3
EC 2.7.4.6
NDK
NM_198175 NP_937818     NDK

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M36981 AAA36369 Q6FHN3
P22392
EC 2.7.13.3
EC 2.7.4.6
L16785 AAA60228 Q6FHN3
P22392
EC 2.7.13.3
EC 2.7.4.6
BC000293 AAH00293 P15531 EC 2.7.4.6
BC002476 AAH02476 Q6FHN3
P22392
EC 2.7.13.3
EC 2.7.4.6
BC018994 AAH18994 P15531 EC 2.7.4.6
BC095458 AAH95458 Q6FHN3
P22392
EC 2.7.13.3
EC 2.7.4.6
BC107894 AAI07895 Q32Q12  
BC133029 AAI33030 P22392 EC 2.7.13.3
EC 2.7.4.6
BC133031 AAI33032 P22392 EC 2.7.13.3
EC 2.7.4.6
AF487339 AAO85436 P15531 EC 2.7.4.6
BT007045 AAP35694 Q6FHN3
P22392
EC 2.7.13.3
EC 2.7.4.6
DQ109675 AAZ82097 P22392 EC 2.7.13.3
EC 2.7.4.6
D28391 BAA05757    
AK291105 BAF83794 P15531 EC 2.7.4.6
AK313448 BAG36237 Q6FHN3  
X17620 CAA35621 P15531 EC 2.7.4.6
X73066 CAA51527 P15531 EC 2.7.4.6
X58965 CAB37870 Q6FHN3
P22392
EC 2.7.13.3
EC 2.7.4.6
CR541718 CAG46519 Q6FHN3
P22392
EC 2.7.13.3
EC 2.7.4.6
CR542104 CAG46901 P15531 EC 2.7.4.6
CR542115 CAG46912 P15531 EC 2.7.4.6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NME2 NP_001018147 R.norvegicus Nme2 83782   NP_114021 98
M.musculus Nme2 18103 Gene Info NP_032731 98
C.elegans F25H2.5 172939   NP_492761 69
N.crassa NCU04202 3877285   XP_961162 63
S.cerevisiae YNK1 853798   NP_012856 61
S.pombe ndk1 2543111   NP_592857 57

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta