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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. STAT3, Signal transducer and activator of transcription 3 (acute-phase response factor)
Sequence ID:NM_139276
NM_003150
NM_213662
RefSeqGene ID:NG_007370
Entrez Gene ID:6774
Ensembl ID:ENSG00000168610

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q21.31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 40467764 - 40500534

 Exon Info From UCSC:
NM_139276
NM_003150
NM_213662

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3347434Full LengthBC000627signal transducer and activator of transcription 3 (acute-phase response factor)
4909141Full LengthBC014482signal transducer and activator of transcription 3 (acute-phase response factor)
3614611IncompleteBC008044signal transducer and activator of transcription 3 (acute-phase response factor)
5539333IncompleteBC067119signal transducer and activator of transcription 3 (acute-phase response factor)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_644805  NP_998827  NP_003141  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003150 NP_003141   SH2
STAT_alpha
STAT_bind
STAT_int
NM_139276 NP_644805 P40763 SH2
STAT_alpha
STAT_bind
STAT_int
NM_213662 NP_998827   SH2
STAT_alpha
STAT_bind
STAT_int

Related Sequences

 
mRNAGenPeptSwissProt
L29277 AAA58374 P40763
AF029311 AAB84254 P40763
BC000627 AAH00627 P40763
BC014482 AAH14482 P40763
EU446657 ABZ92186  
EU831531 ACE86450  
EU831439 ACE87126  
AK291933 BAF84622 P40763
AK297994 BAG60302 B4DNP0
AK301200 BAG62778 B4DVR6
AB451232 BAG70046 B5BTZ6
AK316139 BAH14510 B7ZA24
AJ012463 CAA10032 P40763
AM393108 CAL37986  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens STAT3 NP_003141 R.norvegicus Stat3 25125   NP_036879 100
M.musculus Stat3 20848 Gene Info NP_998825 100

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta