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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. WWOX, WW domain containing oxidoreductase
Sequence ID:NM_016373
NM_130791
NM_130844
NM_018560
NM_130788
NM_130790
NM_130792
RefSeqGene ID:NG_011698
Entrez Gene ID:51741
Ensembl ID:ENSG00000186153

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ESOPHAGEAL CANCER, SOMATICDEC1
DLEC1
LZTS1
RNF6
TGFBR2
TGFBR2

Cytogenetic Location (from UniGene)

Cytogenetic Location:16q23.3-q24.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 78133603 - 78312597

 Exon Info From UCSC:
NM_016373
NM_130791
NM_130844

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3535809Full LengthBC003184WW domain containing oxidoreductase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_057457  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_016373 NP_057457 Q9NZC7 adh_short
WW
NM_130791 NP_570607    
NM_130844 NP_570859    

Related Sequences

 
mRNAGenPeptSwissProt
U13395 AAA21465 Q12953
AF211943 AAF27049 Q9NZC7
AF187015 AAF31694  
AF227526 AAF82053 Q9NZC7
AF227527 AAF82054 Q9NZC7
AF227528 AAF82055 Q9NZC7
AF227529 AAF82056 Q9NZC7
BC003184 AAH03184 Q9NZC7
AF395123 AAK81727 Q9NZC7
AF395124 AAK81728 Q9NZC7
BT007445 AAP36113 Q9NZC7
AY256821 AAP94227 Q9NZC7
AK290438 BAF83127 Q9NZC7
AK291300 BAF83989 A8K5I5
AK027626 BAG51361 B3KNJ9
AK298322 BAG60575 B4DPG3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens WWOX NP_057457 R.norvegicus Wwox 292041   NP_001099658 95
M.musculus Wwox 80707 Gene Info NP_062519 94
D.melanogaster Wwox 34090   NP_609171 51
A.gambiae AgaP_AGAP008423 1277554   XP_317022 50
C.elegans K10H10.6 187285   NP_497012 38
C.elegans dhs-8 175108   NP_001022250 37
C.elegans E04F6.15 184041   NP_495501 37
C.elegans dehydrogenase 183970   NP_503155 37
C.elegans dhs-7 174183   NP_495500 36
C.elegans F32A5.8 353400   NP_495516 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)