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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. NAE1, NEDD8 activating enzyme E1 subunit 1
Sequence ID:NM_001018159
Entrez Gene ID:8883
Ensembl ID:ENSG00000159593

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:16q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 66836782 - 66864879

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2964638Full LengthBC000480NEDD8 activating enzyme E1 subunit 1
2964638Full LengthBC013301NEDD8 activating enzyme E1 subunit 1

Protein Infomation

NM_001018159 NP_001018169    
NM_001018160 NP_001018170    
NM_003905 NP_003896 Q13564  

Related Sequences

U50939 AAC50477 Q13564
BC000480 AAH00480 Q13564
BC013301 AAH13301 Q13564
AY197612 AAP35030 Q13564
DQ892741 ABM83667  
DQ895987 ABM86913  
AK312784 BAG35647 Q13564
AK097680 BAG53511 B3KUP9
AK298159 BAH12735 Q13564
AL136798 CAB66732 Q13564

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens NAE1 NP_003896 M.musculus Nae1 234664 Gene Info NP_659180 97
R.norvegicus Nae1 84019   NP_114461 97
D.melanogaster APP-BP1 39244   NP_648435 46
A.gambiae AgaP_AGAP005544 1276227   XP_315544 45
A.thaliana AXL 817802   NP_180800 42
A.thaliana AXR1 839286   NP_172010 40
N.crassa NCU08040 3878817   XP_962710 36
S.pombe uba5 2543075   NP_594376 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)