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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. AKR1C1, aldo-keto reductase family 1, member C1
Sequence ID:NM_001353
Entrez Gene ID:1645
Ensembl ID:ENSG00000187134

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:10p15-p14Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 5032187 - 5046027

NM_001353 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
126750054535005719
26843550081055008272
43655250091185009234
55363050105005010577
63175350110135011135
75486350143925014501
864102950147755014940
1030111250180425018124
1113137850198915020156

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3877178Full LengthBC015490aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
4662654Full LengthBC020216aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
4825338Full LengthBC040210aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001344  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001135241 NP_001128713      
NM_001353 NP_001344 Q04828 EC 1.1.1.149
EC 1.3.1.20
EC 1.1.1.112
Aldo_ket_red
NM_001354 NP_001345 P52895 EC 1.1.1.213
EC 1.3.1.20
Aldo_ket_red
NM_205845 NP_995317 P52895 EC 1.1.1.213
EC 1.3.1.20
Aldo_ket_red

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U05684 AAA16227 Q04828 EC 1.1.1.149
EC 1.3.1.20
EC 1.1.1.112
U05598 AAA20937 P52895 EC 1.1.1.213
EC 1.3.1.20
M86609 AAB02880 Q04828 EC 1.1.1.149
EC 1.3.1.20
EC 1.1.1.112
S68290 AAD14012 Q04828 EC 1.1.1.149
EC 1.3.1.20
EC 1.1.1.112
S68330 AAD14013 P52895 EC 1.1.1.213
EC 1.3.1.20
BC007024 AAH07024 P52895 EC 1.1.1.213
EC 1.3.1.20
BC015490 AAH15490 Q04828 EC 1.1.1.149
EC 1.3.1.20
EC 1.1.1.112
BC020216 AAH20216 Q04828 EC 1.1.1.149
EC 1.3.1.20
EC 1.1.1.112
BC040210 AAH40210 Q04828 EC 1.1.1.149
EC 1.3.1.20
EC 1.1.1.112
BC063574 AAH63574 P52895 EC 1.1.1.213
EC 1.3.1.20
BT006653 AAP35299 P52895 EC 1.1.1.213
EC 1.3.1.20
BT007197 AAP35861 Q04828 EC 1.1.1.149
EC 1.3.1.20
EC 1.1.1.112
DQ890680 ABM81606    
DQ891484 ABM82410    
DQ893862 ABM84788    
DQ893923 ABM84849    
D26124 BAA05121 Q04828 EC 1.1.1.149
EC 1.3.1.20
EC 1.1.1.112
AB021654 BAA36169 P52895 EC 1.1.1.213
EC 1.3.1.20
AB031083 BAA92883 Q04828 EC 1.1.1.149
EC 1.3.1.20
EC 1.1.1.112
AB031084 BAA92884 P52895 EC 1.1.1.213
EC 1.3.1.20
AB209017 BAD92254 Q59GU2  
AK290304 BAF82993 P52895 EC 1.1.1.213
EC 1.3.1.20
AK296419 BAG59081 B4DK69  
AK296686 BAG59281 P52895 EC 1.1.1.213
EC 1.3.1.20

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AKR1C1 NP_001344 H.sapiens AKR1C2 1646 Gene Info NP_001345 98
M.musculus Akr1c21 77337 Gene Info NP_084177 73
R.norvegicus Akr1c2 291283   NP_001013075 71
A.thaliana AT1G59960 842290   NP_176204 44
A.thaliana AT1G59950 842289   NP_176203 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)