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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MCM4, minichromosome maintenance complex component 4
Sequence ID:NM_005914
NM_182746
RefSeqGene ID:NG_032967
Entrez Gene ID:4173
Ensembl ID:ENSG00000104738

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
NATURAL KILLER CELL AND GLUCOCORTICOID DEFICIENCY WITH DNA REPAIRDEFECT 

Cytogenetic Location (from UniGene)

Cytogenetic Location:8q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 48873533 - 48889551

 Exon Info From UCSC:
NM_005914
NM_182746

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5273457Full LengthBC031061minichromosome maintenance complex component 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005905  NP_877423  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_005914 NP_005905 P33991 EC 3.6.4.12 MCM
NM_182746 NP_877423 P33991 EC 3.6.4.12 MCM

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC031061 AAH31061 P33991 EC 3.6.4.12
AK022899 BAG51132 B3KMX0  
AK296913 BAG59468 B4DLA6  
X74794 CAA52801 P33991 EC 3.6.4.12
AM493756 CAM35476 A4FS09  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MCM4 NP_877423 M.musculus Mcm4 17217 Gene Info NP_032591 95
R.norvegicus Mcm4 29728   NP_387500 95
A.gambiae AgaP_AGAP004956 1275768   XP_315054 63
D.melanogaster dpa 35679   NP_477185 63
C.elegans mcm-4 171793   NP_490962 56
S.cerevisiae MCM4 856130   NP_015344 50
N.crassa NCU02539 3881804   XP_965670 48
A.thaliana MCM4 816142   NP_179236 47
S.pombe cdc21 2539164   NP_588004 46

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta