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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SMG1, smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
Sequence ID:NM_015092
Entrez Gene ID:23049
Ensembl ID:ENSG00000157106

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:16p12.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 18819081 - 18863421

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4797293IncompleteBC047629PI-3-kinase-related kinase SMG-1
5264811IncompleteBC037335PI-3-kinase-related kinase SMG-1
100063073BC156497PI-3-kinase-related kinase SMG-1

Protein Infomation

NM_015092 NP_055907 Q96Q15 EC  

Related Sequences

U32581 AAA86535 Q96Q15 EC
BC156497 AAI56498    
AY014957 AAK00511 Q96Q15 EC
AF186377 AAK58892 Q96Q15 EC
AF395444 AAM73708 Q96Q15 EC
AB007881 BAA24851 Q96Q15 EC
AB061371 BAB70696 Q96Q15 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SMG1 NP_055907 M.musculus Smg1 233789 Gene Info NP_001026984 98
R.norvegicus RGD1563508 691397   XP_002728837 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)