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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PDPK1, 3-phosphoinositide dependent protein kinase-1
Sequence ID:NM_001261816
NM_002613
NM_031268
Entrez Gene ID:5170
Ensembl ID:ENSG00000140992

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:16p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 2587997 - 2647921

 Exon Info From UCSC:
NM_002613
NM_031268

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4079551Full LengthBC0063393-phosphoinositide dependent protein kinase-1
4561371Full LengthBC0121033-phosphoinositide dependent protein kinase-1
5176294Full LengthBC0334943-phosphoinositide dependent protein kinase-1
3451347IncompleteBC0007893-phosphoinositide dependent protein kinase-1
4278655IncompleteBC0125403-phosphoinositide dependent protein kinase-1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_112558  NP_002604  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001261816 NP_001248745      
NM_002613 NP_002604 O15530 EC 2.7.11.1 Pkinase
NM_031268 NP_112558     Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF017995 AAC51825 O15530 EC 2.7.11.1
AF111845 AAF16685 Q9UI25  
BC006339 AAH06339 O15530 EC 2.7.11.1
BC012103 AAH12103 O15530 EC 2.7.11.1
BC033494 AAH33494 O15530 EC 2.7.11.1
DQ892297 ABM83223    
DQ895496 ABM86422    
EU832784 ACE87795    
GQ129441 ACT64575    
AB209835 BAD93072 Q59EH6  
AK222581 BAD96301 Q53HJ9  
AK293900 BAG57287 B4DF26  
Y15056 CAA75341 O15530 EC 2.7.11.1
CR536517 CAG38755 O15530 EC 2.7.11.1
AJ785968 CAH05056 Q6A1A2 EC 2.7.11.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PDPK1 NP_002604 R.norvegicus Pdpk1 81745   NP_112343 96
M.musculus Pdpk1 18607 Gene Info NP_035192 95
D.melanogaster Pk61C 38017   NP_525121 51
A.gambiae AgaP_AGAP001471 1281703   XP_321653 48
A.thaliana PDK1 830330   NP_568138 44
A.thaliana AT3G10540 820219   NP_187665 43
C.elegans pdk-1 180475   NP_001024742 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta