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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. C1S, Complement component 1, s subcomponent
Sequence ID:NM_201442
RefSeqGene ID:NG_011694
Entrez Gene ID:716
Ensembl ID:ENSG00000182326

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:12p13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 7170228 - 7178335

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6199186Full LengthBC056903complement component 1, s subcomponent

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001725  NP_958850  

Protein Infomation

NM_001734 NP_001725 P09871 EC EGF
NM_201442 NP_958850 P09871 EC EGF

Related Sequences

J04080 AAA51852 P09871 EC
M18767 AAA51853 P09871 EC
BC056903 AAH56903 P09871 EC
AK290295 BAF82984 A8K2N0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens C1S NP_001725 R.norvegicus C1s 192262   NP_620255 76
M.musculus Gm5077 317677 Gene Info NP_776289 75
M.musculus C1s 50908 Gene Info NP_659187 74

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta