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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. IGFBP3, insulin-like growth factor binding protein 3
Sequence ID:NM_000598
NM_001013398
RefSeqGene ID:NG_011508
Entrez Gene ID:3486
Ensembl ID:ENSG00000146674

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7p13-p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 45951955 - 45952627

 Exon Info From UCSC:
NM_000598
NM_001013398

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3506666Full LengthBC000013insulin-like growth factor binding protein 3
3506929Full LengthBC018962insulin-like growth factor binding protein 3
4850456Full LengthBC064987insulin-like growth factor binding protein 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001013416  NP_000589  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000598 NP_000589 P17936 Thyroglobulin_1
IGFBP
NM_001013398 NP_001013416   Thyroglobulin_1
IGFBP

Related Sequences

 
mRNAGenPeptSwissProt
M31159 AAA52541 P17936
BC000013 AAH00013 P17936
BC018962 AAH18962 P17936
BC064987 AAH64987 P17936
AF370418 AAQ15254 Q71RC0
DQ884396 ABI63363 A6XNC9
DQ884397 ABI63364 A6XND0
DQ884398 ABI63365 A6XND1
DQ895344 ABM86270  
AK127537 BAC87023 Q6ZSD0
AK315668 BAG38033  
AK056274 BAG51662 B3KPF0
AK075483 BAG52153 B3KPF0
AK091706 BAG52402 B3KPF0
AK091745 BAG52410 B3KRJ8
AK092447 BAG52553 B3KRZ1
AK095869 BAG53151 B3KPF0
AK095900 BAG53162 B3KTQ0
AK095974 BAG53182 B3KTS0
AK095991 BAG53189 B3KTS7
AK122873 BAG53771 B3KVF9
AK123735 BAG53948 B3KVY6
AK125224 BAG54169 B3KWK7
AK297767 BAG60115 B4DN53
AK298143 BAG60419 B4DP07
X64875 CAA46087 P17936

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IGFBP3 NP_001013416 R.norvegicus Igfbp3 24484   NP_036720 82
M.musculus Igfbp3 16009 Gene Info NP_032369 82

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta