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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SMG6, Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)
Sequence ID:NM_017575
NM_001256827
NM_001256828
Entrez Gene ID:23293
Ensembl ID:ENSG00000070366

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 1963137 - 2207069


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100015319BC148373Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001256827 NP_001243756    
NM_001256828 NP_001243757    
NM_017575 NP_060045 Q86US8  

Related Sequences

 
mRNAGenPeptSwissProt
BC064916 AAH64916 Q86US8
BC148373 AAI48374 Q86US8
AY145883 AAN46114 Q86US8
AY168921 AAO17581 Q86US8
AB018275 BAA34452 Q86US8
AK024131 BAB14835 Q9H7Y8
AK302964 BAH13860 B7Z874
AL133597 CAB63733 Q86US8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SMG6 NP_060045 M.musculus Smg6 103677 Gene Info NP_001002764 91
R.norvegicus Smg6 287522   NP_001099278 91
D.melanogaster Smg6 42994   NP_651321 30

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)