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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PSMA6, Proteasome (prosome, macropain) subunit, alpha type, 6
Sequence ID:NM_002791
RefSeqGene ID:NG_011703
Entrez Gene ID:5687
Ensembl ID:ENSG00000100902

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
MYOCARDIAL INFARCTIONESR1
F13A1
F7
GCLC
GCLM
ITGB3
LGALS2
LRP8
LTA
MIAT
OLR1
THBD
TNFSF4

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 35781948 - 35786678

NM_002791 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11853576157335761757
1862803577719935777293
2813623577811935778200
3635183577994535780100
5196973578208635782264
6987923578356635783660
79310113578645435786672

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3542966Full LengthBC002979proteasome (prosome, macropain) subunit, alpha type, 6
4278372Full LengthBC017882proteasome (prosome, macropain) subunit, alpha type, 6
4292526Full LengthBC022354proteasome (prosome, macropain) subunit, alpha type, 6
4869452Full LengthBC023659proteasome (prosome, macropain) subunit, alpha type, 6
6458246Full LengthBC070137proteasome (prosome, macropain) subunit, alpha type, 6

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002782  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002791 NP_002782 P60900 EC 3.4.25.1 Proteasome

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC002979 AAH02979 P60900 EC 3.4.25.1
BC017882 AAH17882 P60900 EC 3.4.25.1
BC022354 AAH22354 P60900 EC 3.4.25.1
BC023659 AAH23659 P60900 EC 3.4.25.1
BC070137 AAH70137 P60900 EC 3.4.25.1
DQ892346 ABM83272    
DQ895551 ABM86477    
D28434 BAA05800    
AK313011 BAG35846 P60900 EC 3.4.25.1
AK298920 BAG61026 B4DQR4  
AK302008 BAG63411 B4DXJ9  
AK316223 BAH14594 B4DQR4  
X59417 CAA42052 P60900 EC 3.4.25.1
X61972 CAA43964 P60900 EC 3.4.25.1
CR456944 CAG33225 P60900 EC 3.4.25.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PSMA6 NP_002782 R.norvegicus Psma6 29673   NP_058979 100
M.musculus Psma6 26443 Gene Info NP_036098 100
A.gambiae AgaP_AGAP003935 1278761   XP_318387 74
D.melanogaster Prosalpha1 45780   NP_524837 67
D.melanogaster CG30382 246582   NP_724616 67
A.thaliana PAA1 833524   NP_198409 64
A.thaliana PAA2 815135   NP_178641 63
N.crassa NCU10061 3874054   XP_957907 63
S.pombe SPBC646.16 2541139   NP_595374 59
C.elegans pas-1 179941   NP_506571 57
S.cerevisiae SCL1 852873   NP_011504 56

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)