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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GSK3B, Glycogen synthase kinase 3 beta
Sequence ID:NM_002093
NM_001146156
RefSeqGene ID:NG_012922
Entrez Gene ID:2932
Ensembl ID:ENSG00000082701

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:3q13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 119545637 - 119812281

 Exon Info From UCSC:
NM_002093
NM_001146156

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3357620Full LengthBC000251glycogen synthase kinase 3 beta
3637163Full LengthBC012760glycogen synthase kinase 3 beta

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002084  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001146156 NP_001139628 P49841 EC 2.7.11.1
EC 2.7.11.26
 
NM_002093 NP_002084     Pkinase
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L33801 AAA66475 P49841 EC 2.7.11.1
EC 2.7.11.26
BC000251 AAH00251 P49841 EC 2.7.11.1
EC 2.7.11.26
BC012760 AAH12760 Q6FI27
P49841
EC 2.7.11.1
EC 2.7.11.26
AY123976 AAM88578 Q86TM2  
DQ892501 ABM83427    
DQ895714 ABM86640    
EU302497 ABX89591 Q6FI27  
AK290897 BAF83586 Q6FI27  
AB451356 BAG70170 B5BUC0  
CR536510 CAG38748 Q6FI27
P49841
EC 2.7.11.1
EC 2.7.11.26

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GSK3B NP_002084 R.norvegicus Gsk3b 84027   NP_114469 99
M.musculus Gsk3b 56637 Gene Info NP_062801 99
C.elegans gsk-3 173149   NP_493243 78
A.gambiae AgaP_AGAP004443 1274587   XP_313732 76
D.melanogaster sgg 31248   NP_476716 73
A.thaliana SK13 831316   NP_196968 68
P.falciparum PfGSK-3 814439   XP_001351197 56

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta